An optical transmission module of the invention uses a semiconductor chip forming an optical modulator integrated laser on a semi-insulating semiconductor board. A query optimizer is provided to determine when it is economical to partially pre-aggregate data records and when it is not. A centrally aligned hole is positioned close to the front edge of the blade member. A generating device allocates the selective operation blocks to the one channel and systematically executes the allocated selective operation blocks according to the algorithm so as to compute the waveform to thereby generate the musical tone through the channel. The content information relating to tracks in the segment is compared with previous user input to select tracks within the segment to be recorded. In addition, low cost adjuvants for enhanced immunogenic response are provided.