The present invention provides methods of use of polyphenol compounds for treating, preventing, mitigating and delaying ischemia or a condition where ischemia occurs. The processing device is operable to generate a first estimated spreading sequence of the signal, and to correlate the first estimated spreading sequence and the confidence vector to generate a second spreading sequence for despreading the signal. The one or more documents retrieved by the search may then be provided to the user or some other recipient.