This invention relates to novel compounds which are inhibitors of T790M containing EGFR mutants, to pharmaceutical compositions containing them, to processes for their preparation, and to their use in therapy for the prevention or treatment of cancer. A globally unique Uniform Resource Identifier, referred to as a Universal Global Title, may be assigned as the address of the Internet telephony endpoint. A digital evaluation circuit with which the statistical evaluation of the output signals generated by the comparators can be carried out is linked to the outputs of the comparators of the analog-to-digital converter. In operation, the laser generates pulses having a durations between 5 and 100 msec and fluences between 10 and 50 Jcm2. The first and second concentration gradient portions have gradients of concentrations of nickel, manganese, and cobalt in the direction from the center to the surface, and the first concentration maintained portion has constant concentrations of nickel, manganese, and cobalt between the first concentration gradient portion and the second concentration gradient portion. The layer of material for the linear structures is etched using the spacer-based etch mask to form the linear structures.