The invention provides novel, substituted 3-arylamino pyridine compoundspharmaceutically acceptable salts, solvates and prodrug compounds thereof, wherein W, R1, R2, R9, R10, R11, R12, R13, R14 are as defined in the specification. The sample support structures are useful for supporting samples for analysis using microscopic techniques, such as electron microscopy, optical microscopy, x-ray microscopy, UV-VIS spectroscopy and nuclear magnetic resonance techniques. Residual analysis is both more robust and more sensitive than conventional univariate range checking on vital signs. A plurality of cooling channels extend essentially parallel between the first inner wall and the second outer wall, and at least one damping volume bordered by cooling channels. Other embodiments may be described and claimed.