Disclosed are compounds of the formula I or a stereoisomer, tautomer, or pharmaceutically acceptable salt or solvate thereof, wherein U, W, A, R, R1, R2, R6a and R7, are as defined in the specification; and pharmaceutical compositions comprising the compounds of formula I. The thermal spray coating method includes positioning a covering on a cooling channel of a component, and thermal spraying a feedstock onto the covering. The dedicated DVD remote control transmitter has DVD player function control buttons and is incapable of controlling all of the game functions of the video game console. The elongated channel member is disposed on the water side portion of the deck between the pair of pontoons. The anticipated demand is determined based at least on information that is not particular to any single access requestor. Based on the determination made by applying logic, the data is sent to the second system in a manner that is associated with the identifier for the entire data.