The present invention relates to a technique for analyzing a sample by utilizing a double integration circuit for outputting a physical quantity related to the output from an analytical tool. The device includes a heat-transfer member conveying heat to the biotissue, a heat-generating chip including a heat-generating member, a first temperature-measuring module, a temperature-measuring element disposed on the heat-transfer member, a second temperature-measuring module, and a controller. The diaphragm layer includes a first layer having at least one heating element configured to sense energy content in a fuel, wherein the heating element includes a doped poly-silicon carbide that is disposed on the substrate. The dispensing head has at least one passageway that receives liquid from an associated one of the base conduits.