Certain tetracyclic compounds are described, which may be used in pharmaceutical compositions and methods for treating disease states, disorders, and conditions mediated by fatty acid amide hydrolase activity. The transmission apparatus starts to transmit the data broadcasting content relating to the program 2, before the time t0 when audiovisual data should change from the program 1 to 2, and transmits the presentation start instruction message at t0. The invention further provides VGF pharmaceutical compositions and methods for the diagnosis, treatment, amelioration, andor prevention of diseases, conditions, and disorders associated with VGF polypeptides.