The present invention provides methods of treating an RNA viral infection, generally involving administering an agent that reduces the activity of a host cell protein required for maturation of a viral protein, where the emergence of variant virus resistant to the agent is reduced. The end member is provided with a separable grip member for being gripped when the seal member is removed, which grip member is connected with one end portion of the seal member in a lengthwise direction thereof, and the seal member is passed through a through hole formed in the grip member to be heated and fixed on the grip member. The scanning unit includes first and second radiation blocking plates having first and second two-dimensional arrays of openings, respectively, wherein the array of pixels and the first and second arrays of openings have a same pitch. Each text segment in the first language may include one or more sentences. An openable basket includes a frame having a sidewall extending circumferentially around the axis, and a bottom movable with respect to the frame from a closed position to an open position to open the basket and facilitate removal of debris. Nanoparticles having phospholipid coatings were found to display improved responses relative to nanoparticles having other coatings that do not promote localization or attraction to membranes.