Data defining an avatar is received over a network. The upper chip is flip-chip bonded to the upper surface of the substrate and the lower chip is accommodated in the opening and flip-chip bonded to the upper chip. The antenna tuner includes a first capacitive element that is coupled to series resonate with the antenna and a low-pass pi network. A detector extracts the alignment information from the image rotation interferometer. In certain embodiments of the systems and methods, a blood sample is treated with hydrostatic pressure, a pulsed electrical field, a pharmaceutical agent, microwave, centrifugation, sonification, radiation, or a combination thereof, under environmental conditions that are effective for the treatment.