The invention relates to a dispensing device for the substantially simultaneous delivery of at least two preparations, different from each other, from a package. The nano-sized zinc oxide particles can be used to either improve cold start performance of internal combustion engines or lower a flash point temperature of a liquid fuel. The detachable portion is connected at least to the side and end walls by a detachable connection to be detached from the carton to define an opening for exposing at least an endmost article for removal. An efficient and bright autostereoscopic display system can be achieved. The controller preferably cooperates with the wireless communications device to generate a sequence of alert message notifications for the user, and for canceling any remaining alert message notification of the sequence based upon a cancellation command response from the user having already received the alert message notification. The invention also relates to use of a compound able to modulate the activity or amount of OE-1 andor OE-2 andor OE-3 in preparation of a medicament for the treatment or prevention of atherosclerosis, dyslipidemia, IRS, and type 2 diabetes.