Disclosed herein is a method of manufacturing a thin film transistor including titanium oxides as an active layer and the structure of the thin film transistor film manufactured using the method. The bicycle-holding apparatus can be switched between a concealed position and an exposed position. The waveguide core may include a material with an anisotropic dielectric permittivity, with the optical axis of the material primarily aligned with direction of light propagation. The pattern is visible in the layer containing the two or more plastic extrudants because an at least one of the plastic extrudants is at least partially transparent. The central resin member includes a resin layer extending in the direction perpendicular to the center axis. In some embodiments, the drug depot provided can include an effective amount of at least analgesic andor at least one anti-inflammatory agent at or near a target site, and can reduce, prevent or treat inflammation andor pain.