The invention provides compounds, pharmaceutical compositions, and methods for the treatment of thromboembolic disorders, such as, for example, arterial cardiovascular thromboembolic disorders, venous cardiovascular thromboembolic disorders, or thromboembolic disorders in the chambers of the heart. The ring seal defines a plurality of lines substantially parallel to the perimeter of the ring seal along which the seal is adapted to seal against a surface of the index cover and to seal against the substantially planar surface of the flow meter body. Drawn by the sub-atmospheric pressure, the liquid saturates the apertured structure of the prosthesis. A fresh stripper liquid is suitably added to the stripper liquid from which the resist components have been removed, and the resultant stripper liquid is reused in the stripping step. A stator, which is disposed within the housing, is configured to rotate at a stator speed. The porosity of the distal portion of the filter body decreases towards the distal end.