A low energy charged particle detector having a diode with a first layer and a top layer physically coupled to the first layer. Pacing pulses are delivered and a return cycle length is measured in response to the plurality of pacing pulses. Writing a top data portion of a predetermined data amount of the data of the file in the first region and writing data of the file in the second region are performed. Meanwhile, if the packet is sent from the sink node to the sensor nodes within a given destination area, after the packet reaches a corresponding destination area, only sensor nodes located within the destination area transmit the packet. Samples are labeled normal for a disease if the concentration of any of the metabolite concentrations or molar ratio concentration do not deviate from the flag threshold, but, in contrast, the sample must be further evaluated if a value is elevated or deficient to some degree. The duration of the integration may be regulated based on the measured times.