Provided herein are compositions and methods for the diagnosis, monitoring, treatment, andor prevention of autoimmune disease based on a causal connection with various epigenetic markers. A performance of a location-based action by a player of a computer-implemented game is associated with a vote on a matter. An information processing portion processes the measured information from the measuring portion to obtain information concerning a blood rheology of the living body. The video codec generates motion information that may be utilized to add an artificial motion blur to each frame of the digital video during processing in a digital video pipeline.