A portable pneumatic fastening tool has an onboard compressor assembly to alleviate the need for an external air compressor. The end effector may be capable of performing workpiece operations. In the present disclosure, allopurinol is used to inhibit xanthine oxidase activity. The methods and devices provide a coating having improved uniformity and coverage which in turn allow for greater control of the amount and dosage of the coating. The Solomanamide analogues of Formula-I or their pharmaceutical salt may be provided in a pharmaceutical composition and administered in an effective amount for the treatment of inflammation andor pain. There also disclose a gate driving circuit and a display device.