Call control methods are disclosed for a multi-zone, packet-based communication system using certain host devices, termed reservation proxy elements, or RPEs to establish reservations of bandwidth for calls on behalf of other participating hosts. The computer-implemented method includes receiving a hierarchical network design for the integrated circuit, wherein the hierarchical design comprises a number of components that are coupled together. The present invention also provides processes for preparing these compounds, pharmaceutical compositions comprising them, methods of treating diseases and the pharmaceutical compositions comprising these compounds.