A polymeric membrane suitable for use in electrophoresis formed from a pre-polymer having a plurality of crosslinkable moieties and the crosslinkable moieties being crosslinked with a polyfunctional crosslinking agent. The signal phase shifting circuit includes a reference signal period dividing circuit having a feedback delay matching array operatively coupled to one of a plurality of voltage control delay lines. There is a sealing member disposed on an inside bottom periphery of the substantially hollow bottomless container member for sealing against an upper portion of such drinking fountain for retaining such cleaning solution. The thrombectomy device further provides for balloon containment and isolation of clot debris from the general circulation, thereby minimizing the risks to a patient of embolic sequelae. In some cases, the base may be programmed to individually auto-configure differing hardware andor software of a plurality of different faceplates when they are respectively coupled to the base. CBH2 that have improved properties compared to the wild type enzyme and methods of using the variants in the hydrolysis of substrates comprising cellulose.