Described herein are methods that can be used for diagnosis and prognosis of breast cancer. The device includes a template body and an absorbent backing attached to the rear side of the template body. If it has been decided that the writing condition that has once been determined by making the write adjustment on such marks that are shorter by one recording unit length needs to be adjusted again, a signal index value that has been defined based on the first recording pattern is set to be a target value. However, the review must be verified for the incentive to be given. The invention also relates to pharmaceutical compositions containing the above compounds and to methods of treating bacterial and protozoal infections in mammals by administering the above compounds.