Proteins and peptides derived from protein ESM-1 are used in the treatment and diagnosis of diseases linked to leukocyte migration. In one embodiment, the system includes a number of image acquisition stations and a number of image review stations all associated with a central server. The method and system further includes collecting ratings and comments associated with each item of information and allowing users to access and sort items of information according to selected rating criteria in order to find the most reliable andor valuable information from the database. The system is used for a data conferencing or class room instructions. The composition, comprising an epitope of a platelet protein, treats diseases by tolerisation.