In the UMTS, semi-static uplink and downlink connection parameters relating to the frequently-used services of voice, fax and web browsing are intermittently broadcast to mobile user equipment which stores the parameters. In an embodiment of the invention, a method for automated composition of geographically relevant media includes receiving a topical query through a search user interface communicatively coupled to a search engine over a data communications network and identifying a particular geographical region of interest within the topical query. A controller provides a control output signal to the flow control device, which may comprise a pinch valve, so as to vary the flow control device output in response to a setpoint signal and measurement signals received from the flowmeter. In a particular embodiment, the expression andor localization of said recombinant polypeptide is restricted to a specific tissue, a single-cell type andor in a particular cellular compartment or domain. In another embodiment, the multi-domain in-plane switching liquid crystal display provides at least two different uniformly aligned liquid crystal domains, for a double multi-domain-In-plane switching LC display.