A method of generating a schema including receiving a data record having a record type name and one or more data values is provided. The topically applied products and methods are intended to be used to enhance any of the transdermal, subdermal, transmembrane, musculoskeletal, transungual, transonychial, andor peronychial deliveries of a therapeutically effective amount of an active ingredient to a patient. In one embodiment, the gamma estimate is limited to only the green color channel, without reference to the gammas for the red and blue channels. for the treatment of skin lesions. The IO controller may comprise a plurality of DMA read request queues, a DMA read slot pool comprising a plurality of DMA read slots, and an expander logic determining a priority of requests in said request queues. A reinforcing member is moveable into contact with the back face of the sealing wall, thereby reinforcing sealing contact between the contact face and the wall surrounding the opening.