1461024916-85ba943e-1f6a-4360-8662-a992592395a6

Novel ethanes substituted with i) a phenyl, ii) a thiazole, and iii) a pyridyl moiety are PDE4 inhibitors. The method includes the steps of fastening the door panel to the door, attaching the substrate to the door panel, and securing the plurality of components to the substrate prior to attaching the substrate to the door panel such that each of the plurality of components is operational upon the substrate being attached to the door panel. The communication paradigm is then used to create an instance of an adapter core for either the initiator or the respondent application.