The present invention relates to a novel method of preventing andor treating neoplasia disorders in a subject that is in need of such prevention or treatment by administering to the subject at least one Cox-2 inhibitor in combination with an EGF receptor antagonist. The water softening unit is disposed between the feed-water unit and the water tub, and is filled with a weak acid cation exchange material having weak acidic cation exchange groups with a pH from 7. The cantilevers serve as springs to support the device and to cushion any temperature stress or bending stress so as not to damage the connection between the device and the metallic leads.