An area detector used in a two-dimensional system is used as a point detector in Bragg-Brentano and other geometries by providing the area detector with a mask the limits the area through which X-rays can enter the detector. Combinations were initially discovered by microarray analysis and selected based upon tumor specificity, relative lack of cross-reactivity with normal tissues, and applicability as targets of multispecific ligands. The connection interface with the anchoring suspension member is characterized by a specially designed surface which is convenient to machine, provides increased surface-to-surface contact area, and provides additional advantages such as improved stress distribution and NVH benefits. The composite nonwoven fabrics of the invention, which have very good isotropic strength. An output is provided of any such one or more failing scan cells determined.