A toroidal plasma source within a substrate processing chamber. The imaging electrostatographic member exhibits improved service life. The targeted protein or degradation product may be identified by selecting a protein known or suspected to be a diagnostic marker for the disease condition, analyzing degradation of the protein in the collected biological sample, and selecting a protein or degradation product that exhibits a measurable half-life at a predetermined period of time. A greater inflow of blood indicates an increasing tumescence whereas a greater outflow of blood indicates a decreasing tumescence.