A dispenser for flowable material adapted for engagement and for dispensing fluid from either a replaceable piston pump reservoir unit comprising a reservoir bottle and a piston pump or a replaceable peristaltic pump reservoir unit comprising a reservoir bottle and a deformable tube member. The air inlet 20 extends from the housing 12 to communicate with an air intake port located at a vehicle location where fresh air is available. The action table may receive the search results and provide an action indication in response to each of the plurality of search results that contain a hit indication. The disclosed model is based on the existence of significant genetic and environmental heterogeneity in complex diseases. The sending terminal generates an instant message to be sent to the receiving terminal, inserts an IMDN request message into the generated instant message, the IMDN request message including a predetermined response limit time, and sends the instant message with the IMDN request message to the receiving terminal through a CPM server.