The invention relates to pharmaceutical formulations of lipophilic therapeutic agents in which such agents are solubilized in largely aqueous vehicles, and processes for preparing and using the same. The multiple pulling members are mounted on the bending portion. Migration is carried out in an automatic manner that allows an application to remain available. The head also includes a second carrier that is coupled to the head and is in selective engagement with a protrusion extending in a recess defined by the first carrier to impart movement in a second direction.