Isothermal work piece holding system uses vibration-damping, low thermal conductivity, low TCE polymer-composite holding body to damp machine tool vibration and chatter while accurately, rigidly maintaining the work piece in position by vacuum andor mechanical clamps during machining. A plurality of movable part fixtures located adjacent to the robot is also provided. Thus the high fidelity PCR products are generated by minimizing the number of doublings of the target nucleic acid sequences during PCR amplification. The invention further relates to a vehicle having such track. In such circumstances, a notional elongate cylindrical profile for the engine is maintained such that a reduced cross section is require for that engine and so allowing a smaller airframe with better sonic boom signature. Changes to the original circuit design made by the optimization are tangibly saved as engineering change orders.