Pyridopyrimidine derivatives represented by the structural formula : wherein, R1, R2 and R3 are defined herein, pharmaceutical acceptable addition salts, stereochemical isomeric forms, N-oxides, solvates and pro-drugs thereof, for use in the treatment of hepatitis C. The methods include treating inappropriate muscle contraction, and treatments for cosmetic purposes. The encoding means generates the transmitted word by adding check information generated based on a parity check matrix expressing a spotty-byte error control code and the input information data to the input information data. The enclosure member is secured to the circuit board so as to form a fluid tight barrier of a compartment defined at least in part by the enclosure member. A set of candidates related to the selected partial match may then be presented for user selection.