The present invention provides a system and methods for managing large user selections in an application. A substrate is connected to the antenna. The invention also provides for methods of treating such subjects with an anti-inflammatory agent or anti-coagulant agent based on the subject’s genotype. First and second springs engage the end faces of the piston and bias the piston and thereby the steering member in first and second axial directions toward a straight ahead position. The roller further includes a locking member disposed in both the third aperture and the aperture of the shaft that prevents the shaft from rotating relative to the body.