The present invention provides compounds, pharmaceutical compositions and methods for the treatment of specific cancers. In particular, one embodiment of the crossbar receives multimedia data at a first throughput from a source operating in a first pipeline stage. Preferably, the injection tube is formed as a cone-shaped funnel with a taper of generally decreasing radius in a distal direction. Therefore, the driver is not inclined to further depress the pedal, thereby preventing the premature activation of the hydraulic braking system. The abuse-deterrent composition retards the release of drug, even if the physical integrity of the formulation is compromised and the resulting material is placed in water, snorted, or swallowed. 06 and the novel La,Al substituted barium strontium titanate solid solution ferroelectric compositions with the formula 1\u2212xLaxTi1\u2212x4\u22123a4Ala}4O3 wherein } denotes a vacancy, y is greater than zero and less than about 0.