A method of phase shifting bits in a digital signal pattern combines a bit-wise phase-shift signal with an external clock signal to produce a perturbed clock signal. Methods of forming such polycrystalline composites that include integrating or mixing a plurality of nanotube materials with diamond or cubic boron nitride particle andor refractory or binder particles are also disclosed. Therefore when the chemical solution is to be drained out from the inner bath, the draining of the chemical solution into the first draining pipe can be quickly done with the aid of the suction force. 3 sigma, and combinations of such genes serve as markers of breast malignancy. The keratin solution thus formed is poured onto a flat surface and allowed to air dry into a thin keratin film.