This invention relates to an enzyme containing granular composition comprising: a) an enzyme containing core and b) a protective substantially continuous layer or coating encapsulating the core comprising at least 60% of a water soluble compound, having a molecular weight below 500 grams per mole, a pH below 11 and a constant humidity at 20 C. The thrombopoietin is administered in a concentration such that the subject’s platelet count or production of platelets is not significantly affected. A first recessed end and a second recessed end are respectively formed on the body and the retaining member so as to firmly sandwich the bar between the first and second recessed ends. The pyrotechnic composition is adapted for use in a safety device, in particular in a safety device in motor vehicles. The timer event associated with the received data bag is then overridden based on the timer event associated with another data bag in the data store. The tape can be applied directly to the logs, between the logs or to objects positioned within the chink, such as splines, insulation sheeting, or plywood panels.