The present invention relates to derivatives of 4–piperidine or acridine and pharmaceutically acceptable salts thereof, use of these compounds as a medicament and for the manufacture of a medicament for treatment of a disease state which can be alleviated by treatment with a 5-HT2B antagonist. The apparatus consists of a controller that includes all of the necessary electronics needed to drive the laser, monitor its operation with the use of measurement circuits, maintain the laser parameters operating within acceptable limits over temperature and device variations and also control operation of related circuits such as signal amplifiers and Host Computer Interface. Each sentence calculator is associated with a particular algorithm and a set of instructions for determining sentence output data based on the applicable legal framework. The ignition source can be oriented to achieve directional control on the product expansion including radial or axial expansion. Each emitter module has an individual address and including at least one electrical ionizer. The wafers are physically bonded to each other through a relatively simple method, and then electrically connected to through TSVs or butting contact holes.