In some embodiments a method comprises disposing an implant into contact with a first bone portion and into contact with a second bone portion, the implant having a first interface configured to receive a restraining member, and a second interface. The mouthpiece may be fitted with or without lip grooves, which aid a user in the positioning and manipulation of the inhaler. Also disclosed are methods of making various types of polyethylene involving polymerizing ethylene in the presence of hydrogen and a catalyst system containing a support made from a magnesium compound, an alkyl silicate and a monoester.